IPSE, a urogenital parasite-derived immunomodulatory protein, ameliorates ifosfamide-induced hemorrhagic cystitis through downregulation of pro-inflammatory pathways
E. Mbanefo, L. Le, R. Zee, N. Banskota, K. Ishida, L. Pennington, J. Odegaard, T. Jardetzky, A. Alouffi, F. Falcone, M. Hsieh
This study identifies IPSE's mechanism in reducing ifosfamide-induced cystitis by downregulating pro-inflammatory pathways and oxidative stress responses in mouse bladders.
bioRxiv · Aug 3, 2018Immunology