Author

M. Hsieh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

L. Le· 4 shared A. Alouffi· 2 shared E. Mbanefo· 2 shared F. Falcone· 2 shared J. Odegaard· 2 shared K. Ishida· 2 shared L. Pennington· 2 shared R. Zee· 2 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersImmunology

L. Le

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cancer drug discovery as a low rank tensor completion problem

V. Siruvallur Murali, D. Agac Cobanoglu, M. Hsieh, M. Zinn, V. S. Malladi, J. Gesell, N. S. Williams, E. S. Welf, G. V. Raj, M. C. Cobanoglu

This paper frames cancer drug discovery as a low rank tensor completion problem and identifies novel drug candidates through computational methods and experimental validation.

bioRxiv · Mar 8, 2021 · PreprintCancer Biology

A Newly Identified Role for IL-22 in Bladder Immunity

J. Honeycutt, L. Le, Y.-J. Hsieh, M. Hsieh

This study identifies IL-22's role in bladder immunity by showing its importance in epithelial maintenance and bacterial clearance during urinary tract infections.

bioRxiv · Aug 17, 2020 · PreprintImmunology

Interleukin-4 signaling plays a major role in urogenital schistosomiasis-associated bladder pathogenesis

E. Mbanefo, C.-L. Fu, C. Ho, L. Le, K. Ishida, M. Hsieh

This study shows IL-4 signaling is critical for bladder pathology in urogenital schistosomiasis, with IL-4 promoting urothelial proliferation and cell cycle changes.

bioRxiv · Aug 24, 2019Immunology

IPSE, a parasite-derived host immunomodulatory protein, is a promising therapeutic for hemorrhagic cystitis

R. Zee, E. C. Mbanefo, L. Le, L. Pennington, J. Odegaard, T. Jardetzky, A. Alouffi, J. Akinwale, F. Falcone, M. Hsieh

This paper demonstrates that H-IPSEH03, a parasite-derived protein, is effective in treating hemorrhagic cystitis by reducing bladder inflammation and promoting urothelial proliferation.

bioRxiv · Aug 25, 2018Immunology

IPSE, a urogenital parasite-derived immunomodulatory protein, ameliorates ifosfamide-induced hemorrhagic cystitis through downregulation of pro-inflammatory pathways

E. Mbanefo, L. Le, R. Zee, N. Banskota, K. Ishida, L. Pennington, J. Odegaard, T. Jardetzky, A. Alouffi, F. Falcone, M. Hsieh

This study identifies IPSE's mechanism in reducing ifosfamide-induced cystitis by downregulating pro-inflammatory pathways and oxidative stress responses in mouse bladders.

bioRxiv · Aug 3, 2018Immunology