Ribosomal s6 kinase (RSK) is a mediator of aquaporin 2 S256 phosphorylation and membrane accumulation after EGFR inhibition with erlotinib
R. S. E. Babicz, P. W. Cheung, N. Baylor, R. Bouley, D. Brown
This study identifies RSK as the kinase responsible for AQP2 S256 phosphorylation and membrane trafficking induced by erlotinib, distinct from the VP-PKA pathway.
bioRxiv · Dec 6, 2022Physiology