Author

N. Dharan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

B. O'Shaughnessy· 1 shared E. Karatekin· 1 shared S. Thiyagarajan· 1 shared Z. A. McDargh· 1 shared Z. Wu· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperBiophysics

B. O'Shaughnessy

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1 paper

Recent·Most cited

The neuronal calcium sensor Synaptotagmin-1 and SNARE proteins cooperate to dilate fusion pores

Z. Wu, N. Dharan, Z. A. McDargh, S. Thiyagarajan, B. O'Shaughnessy, E. Karatekin

This study shows Synaptotagmin-1 promotes fusion pore dilation by reorienting SNARE complexes through calcium-induced C2 domain insertion, enhancing neurotransmitter and hormone release.

bioRxiv · Mar 8, 2021Biophysics