Deletion of arrestin-3 does not improve compulsive drug- seeking behavior in a longitudinal paradigm of oral morphine self-administration
S. Gooding, L. Felth, R. Foxall, Z. Rosa, I. J. Sall, A. Gaur, K. Ireton, J. Gipoor, M. King, N. Dirks, C. A. Whistler, J. A. Whistler
This study shows that deleting arrestin-3 does not reduce compulsive drug-seeking behavior in mice using morphine, suggesting that endogenous signaling patterns involving arrestin-3 may reduce opioid abuse.
bioRxiv · Mar 30, 2023 · PreprintAnimal Behavior & Cognition