Author

N. Dube

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

C. D. Okafor· 2 shared T. Yu· 2 shared A. Biswas· 1 shared A. D. Biswas· 1 shared B. Jung· 1 shared D. D. Prakashchand· 1 shared H. Dong· 1 shared J. Koneru· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersBiophysics

C. D. Okafor

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Simulations reveal unique roles for the FXR hinge in the FXR-RXR nuclear receptor heterodimer

T. Yu, A. Biswas, N. Dube, C. D. Okafor

The paper uses simulations to study the FXR-RXR heterodimer's structure and shows the hinge's role in DNA binding and interdomain allostery.

bioRxiv · May 29, 2024Biophysics

Nuclear receptor interdomain communication is mediated by the hinge with ligand specificity

S. Hazarika, T. Yu, A. D. Biswas, N. Dube, P. Villalona, C. D. Okafor

This study uses computational and experimental methods to show that the hinge region of FXR mediates ligand-induced interdomain communication.

bioRxiv · Feb 10, 2024Biochemistry

Spontaneous Transmembrane Pore Formation by Short-chain Synthetic Peptide

J. Koneru, D. D. Prakashchand, N. Dube, P. Ghosh, J. Mondal

This paper investigates how a short synthetic β-peptide forms transmembrane pores in lipid bilayers through molecular dynamics simulations, showing sequence-dependent pore formation and membrane disruption.

bioRxiv · Feb 12, 2021Biophysics

Designing Sub-20 nm Nanocarriers for Small Molecule Delivery: Interplay among Structural Geometry, Assembly Energetics, and Cargo Release Kinetics

B. Jung, M. Lim, K. Jung, M. Li, H. Dong, N. Dube, T. Xu

This paper examines how structural geometry, assembly energetics, and cargo release kinetics interact in sub-20 nm nanocarriers, showing that small molecule compatibility and release behavior are influenced by these factors.

bioRxiv · Aug 14, 2020Bioengineering