AR phosphorylation and CHK2 kinase activity regulates IR stabilized AR - CHK2 interaction and prostate cancer survival
H. Q. Ta, N. Dworak, M. L. Ivey, D. G. Roller, D. Gioeli
The paper shows that CHK2 interacts with AR and its kinase activity regulates AR stability and prostate cancer cell survival in response to DNA damage.
eLife · Jun 24, 2020Peer-reviewedCancer Biology