Phosphorylation regulates tau's phase separation behavior and interactions with chromatin
L. S. Abasi, N. Elathram, M. Movva, A. Deep, K. D. Corbett, G. T. Debelouchina
This study shows phosphorylation disrupts tau's ability to undergo phase separation and interact with chromatin, potentially contributing to nuclear dysfunction in Alzheimer's disease.
bioRxiv · Dec 21, 2023Biophysics