CRHR1-mediated Akt activation involves endocytosis and soluble adenylyl cyclase activity
P. A. dos Santos Claro, N. G. Armando, A. Attorresi, K. E. Lindl, M. Silbermins, C. Inda, S. Silberstein
This study shows CRHR1-mediated Akt activation depends on endocytosis and sAC activity, with distinct phosphorylation profiles and functional interactions with ERK1/2 pathways.
bioRxiv · Aug 4, 2022 · PreprintCell Biology