Author

N. G. Ayad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

A. M. Jermakowicz· 1 shared A. M. Kurimchak· 1 shared B. K. Allen· 1 shared F. Bourgain-Guglielmetti· 1 shared H. Pradhyumnan· 1 shared J. Duncan· 1 shared K. J. Johnson· 1 shared M. Affer· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. M. Jermakowicz

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

RAPID RESISTANCE TO BET INHIBITORS IS MEDIATED BY FGFR1 IN GLIOBLASTOMA

A. M. Jermakowicz, A. M. Kurimchak, K. J. Johnson, F. Bourgain-Guglielmetti, S. Kaeppeli, M. Affer, H. Pradhyumnan, R. Suter, W. Walters, M. Cepero, J. Duncan, N. G. Ayad

This study identifies rapid resistance to BET inhibitors in glioblastoma mediated by FGFR1 and shows that co-targeting BET and FGFR1 synergizes to reduce tumor growth.

bioRxiv · Dec 19, 2023Cancer Biology

Kinome-wide activity classification of small molecules by deep learning

B. K. Allen, N. G. Ayad, S. C. Schürer

The paper uses deep learning to predict small molecule inhibition across the human kinome, finding that multi-task neural networks outperform single-task methods.

bioRxiv · Jan 4, 2019 · PreprintPharmacology & Toxicology