Syndecan-1 facilitates breast cancer metastasis to the brain
M. R. Sayyad, M. Puchalapalli, N. G. Vergara, S. Mosticone Wangensteen, M. Moore, L. Mu, C. Edwards, A. Anderson, S. Kall, M. Sullivan, M. Dozmorov, J. Singh, M. O. Idowu, J. E. Koblinski
This study shows that syndecan-1 promotes breast cancer metastasis to the brain by enhancing cell migration across the blood-brain barrier and altering cytokine secretion.
bioRxiv · Mar 5, 2019Cancer Biology