Vasoactive intestinal peptide confers anticipatory mucosal immunity by regulating ILC3 activity
C. Seillet, K. Luong, J. Tellier, N. Jacquelot, R. D. Shen, P. Hickey, V. C. Wimmer, L. Whitehead, K. Rogers, G. Smyth, A. Garnham, M. E. Ritchie, G. Belz
This study shows that vasoactive intestinal peptide (VIP) regulates ILC3 activity to enhance IL-22 production and confer gut protection through the VIP-VIPR2 pathway.
bioRxiv · Aug 8, 2019 · PreprintImmunology