During Aspergillus infection, neutrophil, monocyte-derived DC, and plasmacytoid DC enhance innate immune defense through CXCR3-dependent crosstalk
Y. Guo, S. Kasahara, A. Jhingran, N. L. Tosini, B. Zhai, M. A. Aufiero, K. A. M. Mills, M. Gjonbalaj, V. Espinosa, A. Rivera, A. D. Luster, T. Hohl
The paper shows that pDCs enhance innate immune defense against Aspergillus by amplifying neutrophil activity through CXCR3-dependent crosstalk during infection.
bioRxiv · May 5, 2020Immunology