IgG surface mobility promotes antibody-dependent cellular phagocytosis by Syk and Arp2/3 mediated reorganization of Fcγ receptors in macrophages.
S. Jo, N. M. Cronin, N. P. D. Nurmalasari, J. G. Kerkvleit, E. M. Bailey, B. L. Scott, A. D. Hoppe
This study shows that IgG surface mobility enhances antibody-dependent cellular phagocytosis (ADCP) through Syk and Arp2/3-mediated reorganization of Fcγ receptors in macrophages.
bioRxiv · Jul 12, 2021 · PreprintImmunology