Author

B. L. Scott

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Organism:human· 3 Approach:microscopy & imaging analysis· 3 Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

A. D. Hoppe· 4 shared E. M. Bailey· 3 shared J. G. Kerkvliet· 3 shared J. W. Taraska· 2 shared S. Smith· 2 shared A. Hor· 1 shared A. M. Dickey· 1 shared A. M. Jaramillo· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersCell Biology

A. D. Hoppe

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

IgG surface mobility promotes antibody-dependent cellular phagocytosis by Syk and Arp2/3 mediated reorganization of Fcγ receptors in macrophages.

S. Jo, N. M. Cronin, N. P. D. Nurmalasari, J. G. Kerkvleit, E. M. Bailey, B. L. Scott, A. D. Hoppe

This study shows that IgG surface mobility enhances antibody-dependent cellular phagocytosis (ADCP) through Syk and Arp2/3-mediated reorganization of Fcγ receptors in macrophages.

bioRxiv · Jul 12, 2021 · PreprintImmunology

Sterols lower energetic barriers of membrane bending and fission necessary for efficient clathrin mediated endocytosis

R. H. Anderson, K. L. Sochacki, H. Vuppula, B. L. Scott, E. M. Bailey, M. M. Schultz, J. G. Kerkvliet, J. W. Taraska, A. D. Hoppe, K. R. Francis

This study shows that sterols reduce the energy required for membrane bending and fission during clathrin-mediated endocytosis, and that their depletion impairs this process and affects cellular function.

bioRxiv · Jan 31, 2021Cell Biology

The structural dynamics of macropinosome formation and PI3-kinase-mediated sealing revealed by lattice lightsheet microscopy

S. E. Quinn, L. Huang, J. G. Kerkvliet, J. A. Swanson, S. Smith, A. D. Hoppe, R. B. Anderson, N. W. Thiex, B. L. Scott

This study uses lattice lightsheet microscopy to show that PI3K activity is critical for sealing ruffles into macropinosomes, but not for regulating their morphology.

bioRxiv · Dec 1, 2020Cell Biology

Different Munc18 Proteins Mediate Baseline and Stimulated Airway Mucin Secretion

A. M. Jaramillo, L. Piccotti, W. V. Velasco, A. S. Huerta Delgado, Z. Azzegagh, F. Chung, U. Nazeer, J. Farooq, J. Brenner, J. Parker-Thornburg, B. L. Scott, C. M. Evans, R. Adachi, A. R. Burns, S. M. Kreda, , B. F. Dickey

The paper identifies distinct roles of Munc18 isoforms in baseline and stimulated airway mucin secretion, showing Munc18b's protective role in asthma and cystic fibrosis models.

bioRxiv · Oct 24, 2018Cell Biology

Membrane bending begins at any stage of clathrin-coat assembly and defines endocytic dynamics

B. L. Scott, K. A. Sochacki, S. T. Low-Nam, E. M. Bailey, Q. Luu, A. Hor, A. M. Dickey, S. Smith, J. G. Kerkvliet, J. W. Taraska, A. D. Hoppe

The paper uses advanced imaging techniques to study membrane bending during clathrin-coat assembly and finds that bending occurs at different stages of the process, challenging existing models.

bioRxiv · Jul 13, 2017Cell Biology