The self-peptide repertoire plays a critical role in transplant tolerance induction
E. T. Son, P. Faridi, M. Paul-Heng, M. Leong, K. English, S. H. Ramarathinam, A. Braun, N. Dudek, I. E. Alexander, L. Lisowski, P. Bertolino, D. Bowen, A. W. Purcell, N. Mifsud, A. F. Sharland
This study identifies immunogenic MHC I peptides involved in transplant tolerance by combining genetic engineering, immunopeptidomics, and T cell analysis.
bioRxiv · Nov 9, 2020Immunology