Author

N. Mylrea

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Biochemistry· 1

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Approach:experimental assay· 1

Frequent Co-Authors

B. Guan· 1 shared B. Jones· 1 shared C. Luo· 1 shared C. Pierce· 1 shared C. Wilmot· 1 shared D. Chaudhury· 1 shared R. Kazlauskas· 1 shared R. L. Evans· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

B. Guan

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1 paper

Recent·Most cited

Larger active site in an ancestral hydroxynitrile lyase increases catalytically promiscuous esterase activity

B. Jones, R. L. Evans, N. Mylrea, D. Chaudhury, C. Luo, C. Pierce, B. Guan, W. Gordon, C. Wilmot, R. Kazlauskas

This paper reconstructs an ancestral hydroxynitrile lyase, HNL1, which has a larger active site and increased catalytic promiscuity compared to modern HbHNL.

bioRxiv · Apr 6, 2020Biochemistry