SOCS domain targets ECM assembly in lung fibroblasts and experimental lung fibrosis
C. Magdaleno, D. Tschumperlin, N. Rajasekaran, A. Varadaraj
This study shows the SOCS domain reduces ECM protein accumulation in fibrotic lung myofibroblasts and experimental lung fibrosis by inhibiting collagen and fibronectin fibril formation.
bioRxiv · Feb 14, 2024 · PreprintCell Biology