Author

N. S. Galenkamp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

G. Maglia· 1 shared

Activity by Year

2020-2020 · peak 1/yr

1 paper

Recent·Most cited

Substrate binding and turnover modulate the affinity landscape of dihydrofolate reductase to increase its catalytic efficiency

N. S. Galenkamp, G. Maglia

The paper shows that substrate binding and turnover modulate the affinity landscape of DHFR to enhance catalytic efficiency by inducing allosteric changes and energy-driven conformational switches.

bioRxiv · Apr 14, 2020 · PreprintBiophysics