A programmable and site-specific anchoring system for biophysical analysis of DNA:protein interactions on large topologically closed DNA molecules
N. S. Gilhooly, S. C. Kowalczykowski
The paper develops a method to create topologically closed, supercoiled DNA molecules for biophysical analysis of protein-DNA interactions without requiring additional manipulation.
bioRxiv · May 12, 2023 · PreprintBiophysics