Author

N. Tjandra

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Biochemistry· 1

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Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Roll-Mecak· 1 shared E. K. Keenan· 1 shared H. L. Ball· 1 shared K. K. Mahalingan· 1 shared M. E. Tanner· 1 shared M. Strickland· 1 shared Y. Li· 1 shared Y. Liu· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

A. Roll-Mecak

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1 paper

Recent·Most cited

Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes

K. K. Mahalingan, E. K. Keenan, M. Strickland, Y. Li, Y. Liu, H. L. Ball, M. E. Tanner, N. Tjandra, A. Roll-Mecak

This study identifies active-site residues in TTLL enzymes that determine their specificity for initiating or elongating polyglutamate chains on tubulin, revealing structural basis for their functional specialization.

bioRxiv · Jun 7, 2020Biochemistry