Cross-species analyses reveal RORγt-expressing dendritic cells are a lineage of antigen presenting cells conserved across tissues
H. Narasimhan, M. L. Richter, R. Shakiba, N. E. Papaioannou, C. Stehle, K. Ravi Rengarajan, I. Ulmert, V. Küntzel, E.-L. Stange, A. U. Antonova, L. Klein, D. Dudziak, M. Colonna, N. Torow, M. W. Hornef, , B. U. Schraml
The paper identifies RORγt-expressing dendritic cells as a distinct APC lineage conserved across tissues and species, with functions beyond promoting tolerance.
bioRxiv · May 6, 2024Immunology