Author

H. Narasimhan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

I. Ulmert· 2 shared J. Sun· 2 shared K. Lahl· 2 shared A. Schlitzer· 1 shared A. Shi· 1 shared A. U. Antonova· 1 shared B. Schraml· 1 shared B. U. Schraml· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

I. Ulmert

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4 papers

Recent·Most cited

Cross-species analyses reveal RORγt-expressing dendritic cells are a lineage of antigen presenting cells conserved across tissues

H. Narasimhan, M. L. Richter, R. Shakiba, N. E. Papaioannou, C. Stehle, K. Ravi Rengarajan, I. Ulmert, V. Küntzel, E.-L. Stange, A. U. Antonova, L. Klein, D. Dudziak, M. Colonna, N. Torow, M. W. Hornef, , B. U. Schraml

The paper identifies RORγt-expressing dendritic cells as a distinct APC lineage conserved across tissues and species, with functions beyond promoting tolerance.

bioRxiv · May 6, 2024Immunology

Proximal immune-epithelial progenitor interactions drive chronic tissue sequelae post COVID-19

H. Narasimhan, I. S. Cheon, W. Qian, S. Hu, T. Parimon, C. Zang, P. Chen, J. Sun

This study identifies dysregulated immune-epithelial progenitor interactions in post-viral lung sequelae and shows that targeting IFN-γ, TNF, or IL-1β improves alveolar regeneration and pulmonary function.

bioRxiv · Sep 13, 2023 · PreprintImmunology

Genomic deletion of Bcl6 differentially affects conventional dendritic cell subsets and compromises Tfh/Tfr/Th17 cell responses

H. Xiao, I. Ulmert, L. Bach, J. Huber, H. Narasimhan, I. Kurochkin, Y. Chang, S. Holst, U. Moerbe, L. Zhang, A. Schlitzer, F. Pereira, B. Schraml, D. Baumjohann, K. Lahl

bioRxiv · Aug 10, 2022Immunology

Single cell RNA sequencing reveals mechanisms underlying a senescence-like phenotype of Alveolar Macrophages during Aging

Y. Wu, B. Zhu, R. Zhang, N. P. Goplen, X. Gao, H. Narasimhan, A. Shi, Y. Chen, Y. Li, H. Dong, T. J. Braciale, J. Sun

This study uses single-cell RNA sequencing to show that aged alveolar macrophages exhibit a senescence-like phenotype linked to reduced CBFβ expression and impaired self-renewal.

bioRxiv · Jun 4, 2022 · PreprintImmunology