THE IMPACT OF THE HYDROXYMETHYLCYTOSINE EPIGENETIC SIGNATURE ON DNA STRUCTURE AND FUNCTION
F. Battistini, P. Dans, M. Terrazas, C. L. Castellazzi, G. Portella, M. Labrador, N. Villegas, I. Brun-Heath, C. Gonzalez, M. Orozco
This study investigates how 5-hydroxymethylation of DNA affects DNA structure and function, showing that hmC leads to more rigid DNA and alters MBD binding compared to mC.
bioRxiv · Sep 17, 2020 · PreprintBiochemistry