Author

N. Zhigalova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

A. M. Mazur· 1 shared A. V. Artemov· 1 shared E. B. Prokhortchouk· 1 shared S. Zhenilo· 1 shared

Activity by Year

2016-2016 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperCancer Biology

A. M. Mazur

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1 paper

Recent·Most cited

VHL inactivation without hypoxia is sufficient to achieve genome hypermethylation

A. V. Artemov, N. Zhigalova, S. Zhenilo, A. M. Mazur, E. B. Prokhortchouk

This study shows that VHL inactivation causes genome hypermethylation in normoxia, primarily at AP-1 and TRIM28 binding sites, leading to promoter hypermethylation and reduced gene expression of transcription regulators.

bioRxiv · Dec 12, 2016Cancer Biology