Author

A. V. Artemov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. M. Mazur· 2 shared E. B. Prokhortchouk· 2 shared S. Zhenilo· 2 shared A. Reinhardt· 1 shared A. Sokolov· 1 shared A. Starshin· 1 shared C. Gustafsson· 1 shared D. Gackowski· 1 shared

Activity by Year

2016-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

A. M. Mazur

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell-intrinsic functions of the transcription factor Bhlhe40 in activated B cells and T follicular helper cells restrain the germinal center reaction and prevent lymphomagenesis

R. Rauschmeier, A. Reinhardt, C. Gustafsson, V. Glaros, A. V. Artemov, R. Taneja, R. Mansson, M. Busslinger, T. Kreslavsky

This study shows that Bhlhe40 restrains germinal center reaction in B and T cells, preventing lymphoma by limiting TFH and GC B cell proliferation.

bioRxiv · Mar 12, 2021Immunology

An IDH-independent mechanism of DNA hypermethylation upon VHL inactivation in cancer

A. V. Artemov, S. Zhenilo, D. Kaplun, A. Starshin, A. Sokolov, A. M. Mazur, J. Szpotan, M. Gawronski, M. Modrzejewska, D. Gackowski, E. B. Prokhortchouk

This study shows that VHL inactivation causes genome hypermethylation in kidney cancer cells through 2-hydroxyglutarate accumulation, independent of IDH mutations.

bioRxiv · Dec 9, 2020Cancer Biology

VHL inactivation without hypoxia is sufficient to achieve genome hypermethylation

A. V. Artemov, N. Zhigalova, S. Zhenilo, A. M. Mazur, E. B. Prokhortchouk

This study shows that VHL inactivation causes genome hypermethylation in normoxia, primarily at AP-1 and TRIM28 binding sites, leading to promoter hypermethylation and reduced gene expression of transcription regulators.

bioRxiv · Dec 12, 2016Cancer Biology