Aberrant expression of stress-related Hsrω-n lncRNA contributes to CGG repeat-mediated toxicity in a Drosophila model of FXTAS
Nadeem Ahmed, Mudasir Manzoor Reshi, Anand Kumar Singh, Yulin Jin, Abrar Qurashi
This study identifies Hsr{omega}-n lncRNA as a mediator of CGG repeat toxicity in a Drosophila FXTAS model, showing its overexpression exacerbates neurodegeneration while its reduction alleviates it.
bioRxiv · Aug 14, 2026 · PreprintGenetics