Hepatotoxicity assessment of antimalarial compounds from microorganisms using a liver organ-on-a-chip system
Nadeeya Mad-adam, Htun Aung Kyaw, Intira Poonsawaeng, Pimonrat Ketsawatsomkron, Nantiya Bunbamrung, Pattama Pittayakhajonwut, Chitti Thawai, Kenjiro Muta
This study evaluates the hepatotoxicity of three antimalarial compounds using a liver organ-on-a-chip system, finding that NATPP0604 has a superior safety profile compared to the others.
bioRxiv · Sep 17, 2026 · PreprintPharmacology & Toxicology