Reduced intestinal GLP-1+ cell numbers are associated with an inflammation-related epithelial metabolic signature
Elisabeth Urbauer, Doriane Aguanno, Katharina Kuellmer, Amira Metwaly, Nadine Waldschmitt, Mohamed Ahmed, Sevana Khaloian, Gabriele Hörmannsperger, Julien Planchais, Tobias Fromme, Ryan Balfour Sartor, Harry Sokol, Dirk Haller, Eva Rath
The paper shows reduced GLP-1+ cell numbers in inflamed intestinal tissues of mice and CD patients, linked to an inflammatory metabolic signature affecting epithelial differentiation.
Cellular and Molecular Gastroenterology and Hepatology · Oct 4, 2025Peer-reviewedMolecular Biology