Orbitofrontal-striatal potentiation underlies stimulant induced hyperactivity
Sebastiano Bariselli, Nanami L. Miyazaki, Alexxai V. Kravitz
This study shows that psychostimulants enhance synapses in the orbitofrontal to dorsomedial striatum pathway and increase striatal output in awake mice, linking this plasticity to hyperactivity.
bioRxiv · Oct 13, 2019 · PreprintNeuroscience