Sebastiano Bariselli

This paper identifies the role of somatostatin interneurons in the motor cortex in refining motor programs through adaptive changes in neural activity patterns during task learning and execution.

This study shows chronic alcohol enhances synaptic inputs from the dorsolateral striatum to the substantia nigra pars reticulata, increasing their role in action control.

This study shows that gestational ethanol exposure in mice causes sex-specific striatal deficits in acetylcholine and dopamine function, linked to impaired motor learning and altered receptor modulation.

This study identifies a Superior Colliculus to VTA neural pathway that controls orienting responses to conspecifics by activating specific dopamine neurons.

The paper shows that inhibiting TRPV4 rescues social and circuit deficits in Shank3 mutant mice induced by inflammation.

This study shows that psychostimulants enhance synapses in the orbitofrontal to dorsomedial striatum pathway and increase striatal output in awake mice, linking this plasticity to hyperactivity.

This paper shows that SHANK3 downregulation in the VTA speeds up the extinction of contextual associations formed through social interaction in a CPP paradigm.

This study identifies a role for VTA dopamine neurons in social novelty exploration and links their dysfunction to ASD-like behaviors in mice.