Sphingosine-1-phosphate receptor 3 activation promotes sociability and regulates the expression of genes associated with anxiolytic-like behavior
Jose Castro-Vildosola, Chris-Ann Bryan, Nasira Tajamal, Sai Anusha Jonnalagadda, Akhila Kasturi, Jaqueline Tilly, Isabel Garcı́a, Renuka Kumar, Nathan T. Fried, Tamara J. Hala, Brian F. Corbett
This paper shows that S1PR3 agonists promote sociability and reduce anxiety-like behavior in mice by altering gene expression in the prefrontal cortex.
bioRxiv · Jul 31, 2024 · PreprintNeuroscience