Brian F. Corbett

Pharmacologically inhibiting beta-adrenergic receptors during chronic stress mitigates reductions in anaerobic, short-chain fatty acid-producing bacteria in the gut.

This study examines how chronic social defeat stress affects gut microbiome composition in male, female, and aggressor mice, finding stress-induced dysbiosis with sex-specific correlations.

This paper shows that S1PR3 agonists promote sociability and reduce anxiety-like behavior in mice by altering gene expression in the prefrontal cortex.

This study shows that GR-induced S1PR3 expression reduces social anxiety and stress-induced inflammation by affecting neural coherence in rats.

This study shows that Arc in the pPVT promotes habituation to repeated stress by increasing dendritic spines and enhancing mPFC connectivity.

This study shows that FTY720 increases baseline HPA axis activity and reduces anxiety- and despair-like behaviors in rats by reducing angiogenesis in the medial prefrontal cortex.