DISRUPTION OF SYMPATHETIC OUTFLOW TO INTRA-ABDOMINAL ORGANS EMULATES THE METABOLIC EFFECTS OF SLEEVE GASTRECTOMY IN OBESE MICE
Gary J. Schwartz, Rogerio O. Batista, Natalie R. Lopatinsky, Marko Kraljević, Caroline S. Jiang, Amanda S. Dirnberger, Ana B. Emiliano
This study shows that sleeve gastrectomy (SG) causes degeneration of sympathetic neurons in the celiac-superior mesenteric ganglia (CSMG), which mediates metabolic effects like weight loss and glycemic improvement.
bioRxiv · Oct 17, 2022 · PreprintNeuroscience