The Parkinsons disease associated Leucine-rich repeat kinase 2 affects expression of Transferrin receptor 1 and phosphorylation of key signaling proteins in human iPSC-derived dopaminergic neurons
Natalja Funk, Felix Knab, Marita Munz, Thomas Ott, Thomas Gasser, Saskia Biskup
This study shows that LRRK2 variants affect TfR expression and phosphorylation of GSK-3β and Akt in PD patient-derived dopaminergic neurons.
bioRxiv · May 6, 2025 · PreprintNeuroscience