Felix Knab

This study identifies differentially expressed micro-RNAs in LRRK2 G2019S mutation carriers using induced pluripotent stem cell-derived neurons, showing no linear correlation with LRRK2 activity.

This study shows that LRRK2 variants affect TfR expression and phosphorylation of GSK-3β and Akt in PD patient-derived dopaminergic neurons.

The paper characterizes the proteomic changes in dopaminergic neurons with the LRRK2 G2019S mutation and identifies potential biomarkers for Parkinson's disease.

The paper evaluates extracellular miRNA signatures in plasma and CSF to distinguish LRRK2 mutation carriers from sporadic Parkinson's disease patients and healthy controls.

This paper predicts stroke outcomes in mice using MRI and behavioral data, finding that lesion volume and topology are key predictors of subacute and residual deficits.