Repurposed kinase inhibitors and β-lactams as a novel therapy for antibiotic resistant bacteria
Nathan Wlodarchak, Nathan Teachout, Rebecca Procknow, Jeff Beczkiewicz, Adam Schaenzer, Kenneth Satyshur, Martin Pavelka, Bill Zuercher, Dave Drewry, John-Demian Sauer, Rob Striker
This study identifies kinase inhibitors that can be repurposed to combat antibiotic-resistant bacteria and shows they synergize with beta-lactams to enhance antimicrobial efficacy.
bioRxiv · Oct 7, 2017 · PreprintMicrobiology