Author

Jeff Beczkiewicz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Nathan WlodarchakiD· 2 shared Adam Schaenzer· 1 shared Bill Zuercher· 1 shared Dave Drewry· 1 shared J Muse Davis· 1 shared John Feltenberger· 1 shared John-Demian Sauer· 1 shared Kenneth Satyshur· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

Nathan WlodarchakORCID

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2 papers

Recent·Most cited

Comparative analysis of PknB inhibitors for reactivity and toxicity

Nathan Wlodarchak, Jeff Beczkiewicz, Steven Seitz, Zhengqing Ye, John Feltenberger, J Muse Davis, Rob Striker

This study evaluates the reactivity and toxicity of a PknB inhibitor, YH-8, finding high reactivity with thiolating agents, toxicity in zebrafish, and limited activity against non-tubercular mycobacteria.

bioRxiv · Sep 20, 2018 · PreprintMicrobiology

Repurposed kinase inhibitors and β-lactams as a novel therapy for antibiotic resistant bacteria

Nathan Wlodarchak, Nathan Teachout, Rebecca Procknow, Jeff Beczkiewicz, Adam Schaenzer, Kenneth Satyshur, Martin Pavelka, Bill Zuercher, Dave Drewry, John-Demian Sauer, Rob Striker

This study identifies kinase inhibitors that can be repurposed to combat antibiotic-resistant bacteria and shows they synergize with beta-lactams to enhance antimicrobial efficacy.

bioRxiv · Oct 7, 2017 · PreprintMicrobiology