Intracellular Delivery of Full Length Antibodies via Poly-L-lysine-Coated PEG b PLGA Polymersomes Enables Non-invasive Pulmonary Immunotherapy
Nazar Vida, Naren Vyavahare, Jessica Larsen, Shivani Arora
This paper develops a nanocarrier system using PLL-coated PEG-PLGA polymersomes to deliver full-length antibodies intracellularly via aerosol-mediated uptake, demonstrating enhanced loading efficiency and antibody functionality.
bioRxiv · Sep 16, 2025 · PreprintBioengineering