High cholesterol diet modulates macrophage polarization and liver inflammation during early hepatocellular carcinoma progression in zebrafish
Sofia de Oliveira, Ruth A. Houseright, Alyssa L. Graves, Netta Golenberg, Benjamin G. Korte, Veronika Miskolci, Anna Huttenlocher
This study shows that a high-cholesterol diet changes macrophage polarization and worsens liver inflammation and cancer progression in zebrafish with NAFLD/NASH-related HCC.
bioRxiv · Apr 21, 2018 · PreprintCancer Biology