Deletion of the creatine transporter gene in neonatal, but not adult, mice lead to cognitive deficits.
Kenea C Udobi, Nicholas Delcimmuto, Amanda N. Kokenge, Zuhair I. Abdulla, Marla K. Perna, Matthew R. Skelton
This study shows that deleting the creatine transporter gene in neonatal mice causes cognitive deficits, but not in adult mice, indicating Cr's necessity during brain development.
Journal of Inherited Metabolic Disease · Jun 18, 2019Peer-reviewedNeuroscience