Kenea C Udobi

This study develops a mouse model of brainstem cholinergic cell loss to show delayed motor impairments and circuit reorganization in Parkinson's disease.

The paper shows that the SNr and GPe have non-canonical effects on locomotion and reward by differentially inhibiting PPN subpopulations.

This study shows that deleting the creatine transporter in dopaminergic neurons causes hyperactivity in mice without affecting motor function.

This study shows that deleting the creatine transporter gene in neonatal mice causes cognitive deficits, but not in adult mice, indicating Cr's necessity during brain development.

This study creates brain-specific Slc6a8 knockout mice and shows that reduced cerebral creatine causes cognitive deficits without affecting swim speed, unlike ubiquitous knockout mice.