The Pannexin-1 N-terminal Helix Gates a Switch between Ion Conductance and Anandamide Transport
Connor L. Anderson, Nicolas L. Weilinger, Frank Visser, Allison C. Nielsen, Andrew K. J. Boyce, Roger J. Thompson
The paper investigates the dual function of pannexin-1 as an ion channel and anandamide transporter, showing that the N-terminal helix regulates this switch.
bioRxiv · Mar 11, 2024 · PreprintNeuroscience