The ABC transporter Snu drives formation of the lipid-based inward and outward barrier in the skin of Drosophila
Renata Zuber, Michaela Norum, Yiwen Wang, Kathrin Oehl, Davide Accardi, Slawomir Bartozsewski, Nicole Gehring, Jürgen Berger, Matthias Flötenmeyer, Bernard Moussian
The paper identifies the ABC transporter Snu as essential for lipid and cuticulin delivery to the cuticle envelope in Drosophila, establishing a two-step barrier formation mechanism.
bioRxiv · Jul 27, 2017 · PreprintCell Biology