Unique Transcription Factor Functions Regulate Epigenetic and Transcriptional Dynamics During Cardiac Reprogramming
Nicole R. Stone, Casey A. Gifford, Reuben Thomas, Karishma J. B. Pratt, Kaitlen M Samse, Tamer Mohamed, Ethan M. Radzinsky, Amelia Schricker, Pengzhi Yu, Kathryn N. Ivey, Katherine S. Pollard, Deepak Srivastava
This study investigates how Gata4, Mef2c, and Tbx5 drive cardiac reprogramming by analyzing transcriptomic and epigenomic changes in fibroblasts.
bioRxiv · May 20, 2019 · PreprintMolecular Biology