Sympathetic innervation regulates metabolic flexibility of skeletal muscle
Jordan N. Owyoung, HaoMin SiMa, Junwon Heo, Tess Klugherz, Tina M. Tian, Brittney Ward, Nikki Boon, Garrett W. Cooper, Andrew L Hong, Jarrod A. Call, Patricia Jillian Ward
This study investigates how sympathetic innervation affects skeletal muscle metabolic flexibility and finds that denervation impairs mitochondrial function and muscle performance.
bioRxiv · Feb 4, 2026 · PreprintCell Biology