Mind the gap between functional groups and surface of magnetic nanoparticles for highly specific magnetic-based protein assays in biological medium
Rabia Amin, Yihao Wang, Florian Tobias Wolgast, Mohammad Suman Chowdhury, Nina Lehmler, Maren Schubert, Meinhard Schilling, Thilo Viereck, Aidin Lak
This study demonstrates that ultra-dense DNA shells on magnetic nanoparticles enhance antibody conjugation and specificity for detecting SARS-CoV-2 S1 protein in complex biological media.
bioRxiv · Sep 1, 2026 · PreprintBiochemistry