Multiple non-redundant functions underlie the essentiality of lipopolysaccharide in Gram-negative bacteria
Ryan Adam Valdez, Nina Zheng, Sarah D. Beagle, Jiawei Sun, Kerwyn Casey Huang, Petra Anne Levin
This study identifies multiple non-redundant functions of lipopolysaccharide (LPS) in Gram-negative bacteria, showing it is essential for envelope mechanics, membrane biogenesis, and efflux pump activity.
bioRxiv · Oct 22, 2026 · PreprintMicrobiology