Author

Sarah D. Beagle

Washington University in St. LouisORCID 0000-0002-6193-6721Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Petra Anne LeviniD· 2 shared Jiawei SuniD· 1 shared Kerwyn Casey HuangiD· 1 shared Nina Zheng· 1 shared Ryan Adam ValdeziD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersMicrobiology

Petra Anne LevinORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 22, 2026

Multiple non-redundant functions underlie the essentiality of lipopolysaccharide in Gram-negative bacteria

Ryan Adam Valdez, Nina Zheng, Sarah D. Beagle…·Petra Anne Levin

This study identifies multiple non-redundant functions of lipopolysaccharide (LPS) in Gram-negative bacteria, showing it is essential for envelope mechanics, membrane biogenesis, and efflux pump activity.

DOI 10.64898/2026.10.21.760538

E. coliexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivPreprintMar 12, 2025

pH-dependent beta-lactam resistance in Klebsiella pneumoniae is mediated by paralogous class B PBPs and the class A PBP, PBP1b.

Sarah D. Beagle, Petra Anne Levin

This study shows that Klebsiella pneumoniae becomes more resistant to beta-lactam antibiotics at low pH due to the activity of specific penicillin-binding proteins.

DOI 10.1101/2025.03.12.642896

E. coliexperimental assay

𝕏 PostBluesky