Author

Ningyu Ding

Broad Institute

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Molecular Biology· 1

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Andrew E. FirthiD· 1 shared Gary LoughraniD· 1 shared Gionmattia Carancini· 1 shared Irwin JungreisiD· 1 shared Ji Wang· 1 shared Jianchao Zhang· 1 shared John F. AtkinsiD· 1 shared Jonathan M. MudgeiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Andrew E. FirthORCID

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1 paper

Recent·Most cited

Programmed ribosomal frameshifting during PLEKHM2 mRNA decoding generates a constitutively active mediator of kinesin-1-dependent lysosome transport

Gary Loughran, Raffaella De Pace, Ningyu Ding, Jianchao Zhang, Irwin Jungreis, Gionmattia Carancini, Jonathan M. Mudge, Ji Wang, M Kellis, John F. Atkins, Pavel V. Baranov, Andrew E. Firth, Xiaowei Li, Juan S. Bonifacino, Yousuf A. Khan

The paper identifies a programmed ribosomal frameshifting event in PLEKHM2 mRNA that generates a constitutively active protein domain essential for lysosome transport and cardiac function.

bioRxiv · Aug 30, 2024 · PreprintMolecular Biology